Ultrastructural Analysis ofLeishmania infantum chagasiPromastigotes Forms TreatedIn Vitrowith Usnic Acid
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چکیده
منابع مشابه
Ultrastructural Analysis of Leishmania infantum chagasi Promastigotes Forms Treated In Vitro with Usnic Acid
Leishmaniasis is considered by the World Health Organization as one of the infectious parasitic diseases endemic of great relevance and a global public health problem. Pentavalent antimonials used for treatment of this disease are limited and new phytochemicals emerge as an alternative to existing treatments, due to the low toxicity and cost reduction. Usnic acid is uniquely found in lichens an...
متن کاملDoes usnic acid affect microtubules in human cancer cells?
Usnic acid, a lichen metabolite, is known to exert antimitotic and antiproliferative activities against normal and malignant human cells. Many chemotherapy agents exert their activities by blocking cell cycle progression, inducing cell death through apoptosis. Microtubules, protein structure involved in the segregation of chromosomes during mitosis, serve as chemotherapeutical targets due to th...
متن کاملEffect of usnic acid on Candida orthopsilosis and C. parapsilosis.
The activity of usnic acid against Candida orthopsilosis and Candida parapsilosis on planktonic and biofilm conditions was investigated by using a broth microdilution and microplate methods. Potent in vitro activities against different Candida species were obtained. The metabolic activity of sessile cells of C. parapsilosis complex was reduced by 80% at four times the 80% inhibitory concentrati...
متن کاملData on (+)-usnic acid: A new application to treat toxoplasmosis
Toxoplasma gondii pathogen is a threat to human health that results in economic burden. Unfortunately, there are very few high-efficiency and low-toxicity drugs for toxoplasmosis in the clinic. (+)-Usnic acid derived from lichen species has been reported to have anti-inflammatory, antibacterial, anti-parasitology, and even anti-cancer activities. In associated with the published article "Effect...
متن کاملNtp Nomination for Usnic Acid and Usnea Barbata
What is it? • Usnic acid is a complex polycyclic chemical compound produced naturally by certain lichens species. • Lichens containing usnic acid have been used as traditional medicines and crude drugs in other countries. • Usnic acid as a pure substance has been formulated in creams, toothpaste, mouthwash, deodorants and sunscreen products, either as an active principle or a preservative. FDA ...
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ژورنال
عنوان ژورنال: The Scientific World Journal
سال: 2015
ISSN: 2356-6140,1537-744X
DOI: 10.1155/2015/617401